門脈血行の周期的変動について

URI http://harp.lib.hiroshima-u.ac.jp/hbg/metadata/11357
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Title
門脈血行の周期的変動について
Title Alternative
The Influence of Undulatory Changes in the Spleen and Liver Volume,and of the Motility of Alimentary Canals on the Portal Blood Flow
Author
氏名 銭場 武彦
ヨミ センバ タケヒコ
別名 Semba Takehiko
Description

The effects of undulatory changes in the spleen and liver volume, and the effects of tonic and rhythmic contraction of the gut on portal venous flow were investigated in anesthetized dogs. Following results were obtained. 1. The rhythmical contraction of period of 12-57 sec. were observed on the portal vein. It was obtained on extracted preparation and in situ. 2. Active periodic changes in the liver volume caused by injection of Ringer's solution and sod. citrate solution were observed in the dog. Active contraction of liver caused about 10% changes in portal venous pressue. 3. The undulatory changes in the spleen volume effects on the blood flow in the splenic vein. Normal splenic blood flow averaged 27.7 ml/min, but increased to 32.2 ml/min during the period of rhymical contraction of spleen. This increase corresponded to 16.2% of the normal splenic blood flow. 4. Intestinal contraction caused periodicity not only in venous outflow but also in oxygen saturation in venons blood. It was observed in tonic contraction that augmentation of venous outflow synchronized with reduction of oxygen saturation in venons blood and that diminution of venous outflow produced an increase of oxygen saturation in venous blood. In rthythmic contraction, the correlation between venous outflow and oxygen saturation in venous blood could be classified into two patterns. In the first pattern fluctuations of venous outflows corresponded reciprocally to fluctuations of oxygen saturation, and in the second pattern both curves fluctuated parallel to each other. Experiments were also performed influence of the intestinal reflexes on the portal venous flow. It was observed on experiments of cross-circulation system that venous outflow diminished parallel to the loss of intestinal tone during the intestinal inhibitory reflexes, but venouns outflow augmented constantly during the intestinal excitatory reflexes. The mechanisms of the correlation between venous outflow and oxygen saturation in venous blood is discussed on the basis of the particularity of distribution of minute blood vessels and of the autoregulatory systems.

Journal Title
広島文化女子短期大学紀要
Volume
23
Spage
1
Epage
11
Published Date
1990-07-10
Publisher
広島文化女子短期大学
ISSN
09137068
NCID
AN00213869
Language
jpn
NIIType
Departmental Bulletin Paper
Text Version
出版社版
Old URI
Set
hbg