数値計算シミュレーションによる各種左心補助法の心補助効果の検討

URI http://harp.lib.hiroshima-u.ac.jp/hirokoku-u/metadata/5553
File
Title
数値計算シミュレーションによる各種左心補助法の心補助効果の検討
Title Alternative
Study on effect of various assisted circulations using numerical simulation
Author
氏名 工藤 哲
ヨミ クドウ サトル
別名 Kudo Satoru
氏名 徳嶺 朝子
ヨミ トクミネ アサコ
別名 Tokumine Asako
氏名 二宮 伸治
ヨミ ニノミヤ シンジ
別名 Ninomiya Shinji
氏名 福永 信太郎
ヨミ フクナガ シンタロウ
別名 Fukunaga Shintaro
Subject
heart failure
assisted circulation
nonpulsatile flow
pulsatile flow
numerical simulation
Abstract

A heart failure is the pump dysfunction from an impaired cardiac contraction function. At present a heart failure is treated by increasing the preload to the left ventricle with fluid administration and/or decreasing of afterload to the left ventricle with vasodilating drugs and administration of inotropic agents. When recovery of a cardiac contractile function is not sufficent, intraaortic balloon pumping, percutaneous cardiopulmonary support or ventricular assist device are applied. In this paper the effect of various assisted circulation on the failed heart is investigated using numerical simulation with concentrated parameters. Whole body blood flow rate with the RA-Ao(right atrium to aorta) bypass of non-pulsatile flow was 4.87L/min, and those of pulsatile flow in the whole period of diastole, in the early half period of diastole, in the late half period of diastole were 4.93L/min, 4.99L/min,4.93L/min, respectively. The RA-Ao pulsatile flow bypass in the earlier half period of diastole is the most effective for maintaining the whole body blood circulation.

Journal Title
医療工学雑誌
Issue
3
Spage
7
Epage
15
Published Date
2009/3/15
Publisher
広島国際大学大学院総合人間科学研究科医療工学専攻
ISSN
1881-9265
NCID
AA12217173
Language
jpn
NIIType
Departmental Bulletin Paper
Text Version
出版社版
Sort Key
2
Old URI
Set
hirokoku-u