Study on effect of various assisted circulations using numerical simulation
A heart failure is the pump dysfunction from an impaired cardiac contraction function. At present a heart failure is treated by increasing the preload to the left ventricle with fluid administration and/or decreasing of afterload to the left ventricle with vasodilating drugs and administration of inotropic agents. When recovery of a cardiac contractile function is not sufficent, intraaortic balloon pumping, percutaneous cardiopulmonary support or ventricular assist device are applied. In this paper the effect of various assisted circulation on the failed heart is investigated using numerical simulation with concentrated parameters. Whole body blood flow rate with the RA-Ao(right atrium to aorta) bypass of non-pulsatile flow was 4.87L/min, and those of pulsatile flow in the whole period of diastole, in the early half period of diastole, in the late half period of diastole were 4.93L/min, 4.99L/min,4.93L/min, respectively. The RA-Ao pulsatile flow bypass in the earlier half period of diastole is the most effective for maintaining the whole body blood circulation.
Departmental Bulletin Paper